Beuvon F, Varlet P, Fallet C, Trystram D, Daumas-Duport C
Laboratoire d'Anatomie Pathologique, Hôpital Sainte-Anne, Paris.
Clin Exp Pathol. 1999;47(6):286-96.
According to the Ste Anne hospital classification and grading system of oligodendrogliomas the presence of contrast enhancement on MRI and/or the presence of an histological endothelial hyperplasia are correlated with a pejorative prognosis (high grade or grade B). Surgical tumoral exerese and adjuvant chemo or radiotherapy are indicated. When clinical and radiological aspects are typical the extemporaneous diagnosis of oligodendroglioma on smear is usually easy (1). In case of atypical forms: unusual localization or cytological appearance, especially with a small cell hyperchromatic undifferenciated tumor few diagnostic hypothesismay be considered. Four cerebellar tumors are presented with relevant and differential cytological diagnostic criteria. A comparative study between clinical and radiological aspects of medulloblastoma, primitive lymphoma, undifferenciated small cell lung carcinoma, and grade B oligodendroglioma is presented.
根据圣安妮医院少突胶质细胞瘤分类和分级系统，MRI上出现对比增强和/或组织学上存在内皮细胞增生与预后不良（高级别或B级）相关。建议进行手术肿瘤切除及辅助化疗或放疗。当临床和放射学表现典型时，涂片上少突胶质细胞瘤的即时诊断通常很容易（1）。对于非典型形式：定位异常或细胞学表现异常，尤其是小细胞、深染、未分化肿瘤，可能需要考虑几种诊断假设。现介绍4例小脑肿瘤的相关细胞学诊断标准及鉴别诊断标准。还介绍了髓母细胞瘤、原发性淋巴瘤、未分化小细胞肺癌和B级少突胶质细胞瘤临床和放射学表现的比较研究。
