Semlitsch G, Buchinger W, Reiterer E, Binter G, Rainer F
Abteilung für Innere Medizin und Nuklearmedizin des Krankenhauses der Barmherzigen Brüder Graz-Eggenberg.
Acta Med Austriaca. 2000;27(2):54-5.
Thyroid hormone autoantibodies may lead to abnormal values of free triiodothyronine (FT3) and free thyroxine (FT4) by interference with the radio immunoassay (RIA). We examined thyroid function in six patients with known triiodothyronine-binding autoantibodies using a RIA and an electro-chemiluminescence immunoassay (ECLIA). FT3 values measured by RIA were spuriously high, ECLIA measurement of FT3 led to correct values according to the patients' thyroid status. We conclude from these results that in patients with triiodothyronine-binding autoantibodies FT3 measurement by ECLIA is more useful than measurement by RIA.
甲状腺激素自身抗体可能通过干扰放射免疫测定法（RIA）导致游离三碘甲状腺原氨酸（FT3）和游离甲状腺素（FT4）值异常。我们使用RIA和电化学发光免疫测定法（ECLIA）检测了6例已知存在三碘甲状腺原氨酸结合自身抗体患者的甲状腺功能。通过RIA测得的FT3值假性升高，而通过ECLIA测定的FT3值根据患者的甲状腺状态得出了正确结果。我们从这些结果得出结论，对于存在三碘甲状腺原氨酸结合自身抗体的患者，通过ECLIA测定FT3比通过RIA测定更有用。
