Pongratz R, Buchinger W, Semlitsch G, Meister E, Nadler K, Rainer F
Internen Abteilung des Krankenhauses der Barmherzigen Brüder, Eggenberg, Graz.
Acta Med Austriaca. 2000;27(2):58-60.
The frequent occurrence of both rheumatoid arthritis and autoimmune thyroiditis was already investigated with in part many conflicting results. We investigated a number of 792 patients (383 of them suffering from rheumatoid arthritis and 409 with osteoarthritis). In all patients antithyroid peroxidase and antithyroglobulin antibodies were determined. Patients with rheumatoid arthritis showed a significantly higher occurrence of circulating thyroid antibodies than those with osteoarthritis (9.1% versus 3.7%, p = 0.0016). We conclude that there exists a cumulate coincidence of both diseases. Patients suffering from rheumatoid arthritis should undergo a thyroid examination especially for the presence of autoimmune thyroiditis.
类风湿性关节炎和自身免疫性甲状腺炎的频繁并发已经在一定程度上得到了研究，但结果多有冲突。我们调查了792名患者（其中383名患有类风湿性关节炎，409名患有骨关节炎）。对所有患者均测定了抗甲状腺过氧化物酶抗体和抗甲状腺球蛋白抗体。类风湿性关节炎患者循环甲状腺抗体的发生率显著高于骨关节炎患者（9.1%对3.7%，p = 0.0016）。我们得出结论，这两种疾病存在累积性并发情况。患有类风湿性关节炎的患者应接受甲状腺检查，特别是检查是否存在自身免疫性甲状腺炎。
