Alexiu O, Mircea N, Balaban M, Furtunescu B
Anaesthesia. 1975 Sep;30(5):609-15. doi: 10.1111/j.1365-2044.1975.tb00920.x.
Over a 3-year-period 72 patients with upper digestive tract haemorrhage due to peptic ulcer were transfused exclusively with isotonic sodium chloride and glucose solutions in equal quantities. The results are compared with 69 patients treated previously in whom conventional blood transfusion regimes had been used. Transfusion therapy was combined with emergency surgery involving vagotomy and draininage, with surgical haemostasis in situ. There were no significant differences between the two groups with regard to anaesthesia, surgery and post-operative managemement. Apart from anemia, there were less early and late complications in the group not receiving blood. The amount of crystalloid solutions administered varied between 7000 ml and 19,000 ml causing a diuresis of 1000 ml to 5300 ml within the first 24 hours. The use of this transfusion regime for haemodynamic re-equilibration in upper gastro-intestinal haemorrhage due to ulcer, in cases in which haemostasis can be obtained with certainty by emergency surgery, allows transfusion of stored blood and colloid solutions to be avoided and emergency surgery to be safely undertaken at the earliest moment. The severe acute anaemia which is caused appears to create no special problems.
在3年期间，72例因消化性溃疡导致上消化道出血的患者仅输注等量的等渗氯化钠溶液和葡萄糖溶液。将结果与先前接受传统输血方案治疗的69例患者进行比较。输血治疗与包括迷走神经切断术和引流术的急诊手术相结合，并进行原位手术止血。两组在麻醉、手术和术后管理方面没有显著差异。除贫血外，未接受输血的组早期和晚期并发症较少。晶体溶液的用量在7000毫升至19000毫升之间，在最初24小时内引起1000毫升至5300毫升的尿量。对于因溃疡导致的上消化道出血，在可以通过急诊手术确定止血的情况下，使用这种输血方案进行血流动力学重新平衡，可避免输注库存血和胶体溶液，并能尽早安全地进行急诊手术。所导致的严重急性贫血似乎不会产生特殊问题。
