Gothelf D, Levite R, Gadoth N
Geha Psychiatric Hospital, Petah-Tiqwa, Tel Aviv, Israel.
Brain Dev. 2000 May;22(3):184-7. doi: 10.1016/s0387-7604(99)00129-1.
A young male with adrenomyeloleukodystrophy (AMLD), diagnosed at the age of 25 years, presented with signs of bipolar affective disorder (BPD) concomitant with radiological findings of central demyelination. There was a marked deterioration of the earlier relatively benign neurological dysfunction, leading to fatal bulbar syndrome. The association of BPD with central demyelination in AMLD is in agreement with previously reported cases of this and other types of multifocal central demyelination diseases.
一名25岁被诊断患有肾上腺脑白质营养不良（AMLD）的年轻男性，出现了双相情感障碍（BPD）的症状，并伴有中枢性脱髓鞘的影像学表现。其先前相对良性的神经功能障碍明显恶化，导致致命的延髓综合征。BPD与AMLD中的中枢性脱髓鞘之间的关联与先前报道的该病例以及其他类型的多灶性中枢性脱髓鞘疾病相符。
