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人体血管化膝关节移植:头两年的经验

Vascularised knee joint transplantation in man: the first two years experience.

作者信息

Kirschner M H, Brauns L, Gonschorek O, Bühren V, Hofmann G O

机构信息

Trauma Centre Murnau, Murnau/Staffelsee, Germany.

出版信息

Eur J Surg. 2000 Apr;166(4):320-7. doi: 10.1080/110241500750009186.

DOI:10.1080/110241500750009186
PMID:10817331
Abstract

OBJECTIVE

To describe our early experience with a new technique for restoring destroyed knee joints to give reasonable functional results.

DESIGN

Observational clinical trial.

SETTING

Level-1-Trauma centre, Germany.

SUBJECTS

5 patients with large bone defects of the knee and loss of the extensor apparatus caused either by serious injury alone, or infection after serious injury.

INTERVENTIONS

Transplantation of fresh and perfused knee joints with a vascular pedicle from multiorgan donors under immunosuppression.

MAIN OUTCOME AND MEASURES

Ability to walk, need to remove one transplanted joint.

RESULTS

Four patients are able to walk, the range of movement being from 50 degrees-120 degrees. The first patient additionally had to be provided with a total knee joint arthroplasty. In the third patient the graft became infected and had to be removed. She finally had an arthrodesis and bone lengthening by the Ilizarov technique.

CONCLUSIONS

Transplantation of the knee joint may be an alternative to bone lengthening or amputation for patients with total loss of the extensor apparatus.

摘要

目的

描述我们采用一种新技术修复受损膝关节以获得合理功能结果的早期经验。

设计

观察性临床试验。

地点

德国一级创伤中心。

研究对象

5例膝关节存在大的骨缺损且伸肌装置因单纯严重损伤或严重损伤后感染而缺失的患者。

干预措施

在免疫抑制下,移植来自多器官供体的带血管蒂的新鲜灌注膝关节。

主要结局指标

行走能力,是否需要移除一个移植关节。

结果

4例患者能够行走,活动范围为50度至120度。首例患者还需接受全膝关节置换术。第3例患者的移植物发生感染,不得不被移除。她最终通过伊里扎洛夫技术进行了关节融合和骨延长术。

结论

对于伸肌装置完全缺失的患者,膝关节移植可能是骨延长或截肢的一种替代方法。

相似文献

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Vascularised knee joint transplantation in man: the first two years experience.人体血管化膝关节移植:头两年的经验
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