Hart C L, Haney M, Foltin R W, Fischman M W
New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, USA.
Behav Pharmacol. 2000 Feb;11(1):87-91. doi: 10.1097/00008877-200002000-00010.
Six experienced cocaine smokers (two men, four women) participated in an inpatient study to compare self-administration of smoked cocaine when either a $5 money or merchandise voucher was available as an alternative reinforcer. A six-trial choice procedure was used, with sessions consisting of (1) one sample trial, where participants received the cocaine dose and the alternative reinforcer available that day, and (2) five choice trials, where participants chose between the available cocaine dose and the alternative reinforcer. There were eight sessions: in separate sessions, each dose of cocaine (0, 12, 25, 50 mg) was paired with a money voucher and with a merchandise voucher. The choice to self-administer cocaine significantly increased with escalating cocaine doses, and significantly less cocaine was self-administered when money vouchers were available as compared to merchandise vouchers. These data demonstrate that money vouchers are a more effective alternative reinforcer than merchandise vouchers in cocaine abusers.
六名有吸食可卡因经验的人(两名男性,四名女性)参与了一项住院研究,以比较当有5美元现金或商品代金券作为替代强化物时,吸食可卡因的自我给药情况。采用了六次试验的选择程序,每次试验包括:(1)一次样本试验,参与者在该试验中接受当天提供的可卡因剂量和替代强化物;(2)五次选择试验,参与者在可用的可卡因剂量和替代强化物之间进行选择。共有八次试验:在不同的试验中,每种可卡因剂量(0、12、25、50毫克)分别与现金代金券和商品代金券配对。随着可卡因剂量的增加,自我给药可卡因的选择显著增加,与商品代金券相比,当有现金代金券时,自我给药的可卡因显著减少。这些数据表明,在可卡因滥用者中,现金代金券作为替代强化物比商品代金券更有效。