透明变性斯皮茨痣

Hyalinizing Spitz nevus.

作者信息

Lee M W, Choi J H, Sung K J, Moon K C, Koh J K

机构信息

Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.

出版信息

J Dermatol. 2000 Apr;27(4):273-5. doi: 10.1111/j.1346-8138.2000.tb02164.x.

DOI:10.1111/j.1346-8138.2000.tb02164.x

PMID:10824493

Abstract

A seventeen-year-old Korean girl had a reddish-brown papular lesion on the nose. Histopathologically, it proved to be a "hyalinizing Spitz nevus" with the characteristic features of a discohesive growth pattern of nevus cells and hyalinized stroma. Immunohistochemical stains showed positive reactivity of nevus cells with S-100 protein and Vimentin and negative stainings with HMB45, CD68, CEA and low molecular weight cytokeratin. Hyalinizing Spitz nevus may represent a variant in the spectrum of Spitz nevus.

摘要

一名17岁的韩国女孩鼻子上有一个红棕色丘疹性病变。组织病理学检查证实为“透明化斯皮茨痣”，具有痣细胞分离性生长模式和透明化间质的特征。免疫组织化学染色显示痣细胞对S-100蛋白和波形蛋白呈阳性反应，对HMB45、CD68、癌胚抗原和低分子量细胞角蛋白呈阴性染色。透明化斯皮茨痣可能是斯皮茨痣谱系中的一种变体。