Roman K, Rosenthal E, Razavi R
Department of Paediatric Cardiology, Guys Hospital, Guys and St. Thomas NHS Trust, London, UK.
Cardiol Young. 2000 May;10(3):275-8. doi: 10.1017/s1047951100009240.
We report a newborn male who presented with severe central cyanosis on the third day of life. Partial thrombotic obstruction of the pulmonary trunk secondary to Antithrombin III (homozygous defect of heparin binding site) deficiency was subsequently diagnosed. Surgical thrombectomy, and infusions of Antithrombin III concentrate, led to a successful outcome. We postulate that intrauterine thrombosis occurred to give this unusual presentation.
我们报告了一名男性新生儿，其在出生后第三天出现严重的中央性发绀。随后诊断为继发于抗凝血酶III（肝素结合位点纯合缺陷）缺乏的肺动脉主干部分血栓性梗阻。手术取栓及输注抗凝血酶III浓缩剂取得了成功的结果。我们推测子宫内发生了血栓形成，导致了这种不寻常的表现。
