Ashitani J, Kumamoto K, Matsukura S
National Sanatorium Miyazakihigashi Hospital, Miyazaki.
Intern Med. 2000 May;39(5):433-6. doi: 10.2169/internalmedicine.39.433.
We report a case of Paragonimus westermani infection with a reticulonodular lesion in the right lung, left pleural effusion, and a mobile subcutaneous mass. Analyses of pleural effusion and bronchoalveolar lavage fluid (BALF) showed marked eosinophilia and high levels of eosinophil cationic protein and interleukin (IL)-5. Transbronchial lung biopsy revealed the presence of pneumonia with mild eosinophilic infiltration but remarkable lymphocytic infiltration. In this patient, high IL-5 levels in both BALF and pleural effusion could explain the remarkable eosinophilia.
我们报告一例卫氏并殖吸虫感染病例,患者右肺出现网状结节性病变、左侧胸腔积液及可移动的皮下肿物。胸腔积液和支气管肺泡灌洗(BALF)液分析显示显著嗜酸性粒细胞增多以及嗜酸性粒细胞阳离子蛋白和白细胞介素(IL)-5水平升高。经支气管肺活检显示存在肺炎,伴有轻度嗜酸性粒细胞浸润,但淋巴细胞浸润显著。在该患者中,BALF液和胸腔积液中高IL-5水平可解释显著的嗜酸性粒细胞增多。