Hogan A M, Kirkham F J, Isaacs E B
Cognitive Neurosciences Unit, Institute of Child Health, University College London Medical School, UK.
J Child Neurol. 2000 May;15(5):325-32. doi: 10.1177/088307380001500509.
Review of published clinical and neuropsychologic outcome studies reveals limited information about intellectual functioning after childhood stroke. The extant data are supplemented here by analysis of intelligence quotient (IQ) results obtained from 38 children in an ongoing study of unilateral middle cerebral artery ischemic stroke. Evidence so far indicates that, after stroke, mean IQ falls significantly below the population mean but remains within the average range. There is no significant difference between hemispheric side of injury; the Verbal and Performance IQ lateralization profile widely recognized in adults with unilateral injury is not apparent in younger children, and there is only a trend toward this profile in older children. The effects of a number of other variables, including sex, site of stroke, and longitudinal assessment, are also considered. Although the generally minor effect of stroke on IQ is encouraging, a number of children do require extra help on return to school. Some suggestions for future research are highlighted in order to encourage further consideration of the issues raised here.
已发表的临床和神经心理学结果研究综述显示，关于儿童期中风后智力功能的信息有限。在此，通过对一项正在进行的单侧大脑中动脉缺血性中风研究中38名儿童的智商（IQ）结果进行分析，补充现有数据。迄今为止的证据表明，中风后，平均智商显著低于总体平均水平，但仍处于平均范围内。损伤半球侧之间没有显著差异；在单侧损伤的成年人中广泛认可的言语和操作智商的侧化模式在年幼儿童中并不明显，而在年长儿童中只有这种模式的趋势。还考虑了包括性别、中风部位和纵向评估在内的许多其他变量的影响。虽然中风对智商的总体轻微影响令人鼓舞，但一些儿童在重返学校时确实需要额外帮助。为鼓励进一步考虑此处提出的问题，强调了一些未来研究的建议。
