Schwartz M, Holloman T L, Dinno M A, Carrasquer G
Proc Soc Exp Biol Med. 1976 Mar;151(3):523-5. doi: 10.3181/00379727-151-39249.
The presence of ethacrynic acid in the nutrient sulphate solution produces, generally in less than 3 min, a decrease in resistance accompanied by an increase in transmucosal PD. These results strongly suggest that the dominant effect of ethacrynic acid is not on the Na+ pathway of the nutrient membrane, but without further knowledge of the resistance of other ionic pathways, it cannot be inferred whether the effect predominates on the K+ pathway as in Cl- media.
在营养硫酸盐溶液中加入依他尼酸，通常在不到3分钟内，电阻降低，同时跨黏膜电位差增加。这些结果有力地表明，依他尼酸的主要作用并非作用于营养膜的钠离子通道，但在不进一步了解其他离子通道电阻的情况下，无法推断其作用是否像在氯离子介质中那样在钾离子通道上占主导地位。
