Mjåland O, Normann E
Dept. of Surgery, Vestfold Central Hospital, Tønsberg, Norway.
Scand J Gastroenterol. 2000 Apr;35(4):446-8. doi: 10.1080/003655200750024047.
Cope showed in 1957 that pancreatitis may be the presenting symptom in hyperparathyroidism. Since then, the literature has reported a coincidence of primary hyperparathyroidism and pancreatitis between 1% and 19%, but the true relationship has not been fully established. When severe pancreatitis follows parathyroidectomy, a condition familiar to parathyroid surgeons, reports are mostly anecdotal and by many authors considered to be coincidental. We present the case history of a 58-year-old man with a longstanding history of untreated primary hyperparathyroidism who developed severe pancreatitis immediately after removal of a 400-mg parathyroid adenoma. He was the first in a series of 108 operated patients to develop this complication. His preoperative levels of parathormone and serum calcium were the highest in our material. We believe that pancreatitis after parathyroidectomy is a real but rare complication that might be predicted by preoperative high values of serum calcium and parathormone.
科普在1957年指出，胰腺炎可能是甲状旁腺功能亢进的首发症状。自那时起，文献报道原发性甲状旁腺功能亢进与胰腺炎的并发率在1%至19%之间，但二者之间的真正关系尚未完全明确。当甲状旁腺切除术后发生严重胰腺炎时，这是甲状旁腺外科医生熟知的一种情况，相关报道大多是轶事性的，许多作者认为这是巧合。我们介绍一位58岁男性的病例史，他有长期未经治疗的原发性甲状旁腺功能亢进病史，在切除一个400毫克的甲状旁腺腺瘤后立即发生了严重胰腺炎。他是108例接受手术的患者中首例出现这种并发症的。他术前的甲状旁腺激素和血清钙水平在我们的病例资料中是最高的。我们认为甲状旁腺切除术后的胰腺炎是一种真实但罕见的并发症，术前血清钙和甲状旁腺激素的高值可能预示着这种并发症。
