[对由亲水性塑料制成的实验性人工角膜的微生物学研究（作者译）]

[Microbiologic Investigations of experimental keratoprostheses made with hydrophilic plastics (author's transl)].

作者信息

Mester U, Krasemann C

出版信息

Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1976 Jan 16;198(1):79-82. doi: 10.1007/BF00411448.

Abstract

The subject of our investigations is the question: is there an increased risk of infection with eyes operated on keratoprostheses made with hydrophilic soft plastic material (HEMA)? Our first step was an analysis of the normal conjunctival spectrum of microorganism of our rabbits, operated and nonoperated. Then we made exploratory punctures of the anterior chamber of 7 eyes submitted to implantations of HEMA keratoprostheses. During a period of 10 days this puncture exudate was incubated in a culture medium. In 6 out of 7 cases, even after 10 days of incubation, no microorganisms were found. In one case after 72 hours of incubation, a poor growth of a staphylococcus was observed. It can be assumed that in this case the microorganism entered the anterior chamber during the puncture procedure. The results of these investigations confirm the calculation that the "pores" of hydrophilic plastic material are too small for penetration of microorganism.

摘要

我们研究的主题是这个问题

使用亲水性软塑料材料（甲基丙烯酸羟乙酯，HEMA）制作的角膜假体进行眼部手术，感染风险会增加吗？我们的第一步是分析我们的兔子（包括接受手术和未接受手术的）结膜微生物的正常谱。然后，我们对7只接受HEMA角膜假体植入的眼睛进行前房穿刺探查。在10天的时间里，将这种穿刺渗出液在培养基中培养。在7个案例中的6个，即使经过10天的培养，也未发现微生物。在1个案例中，培养72小时后，观察到葡萄球菌生长不佳。可以推测，在这种情况下，微生物是在穿刺过程中进入前房的。这些研究结果证实了这样的计算结果，即亲水性塑料材料的“孔隙”太小，微生物无法穿透。