Reul G J, Cooley D A, Sandiford F M, Kyger E R, Wukasch D C, Hallman G L
Arch Surg. 1976 Apr;111(4):414-8. doi: 10.1001/archsurg.1976.01360220110018.
From 1969 through 1974, a total of 4,522 patients were operated on for coronary artery occlusive disease. This article is an in-depth analysis of a consecutive series of 275 of these patients, operated on during 1974. The mortality was 1.8% and perioperative myocardial infarction occurred in 3.6%. On analysis of risk factors, it was found that 24% of the patients were over the age of 60; 57% had some degree of left ventricular dysfunction; 9% had generalized hypokinesis; 24% were New York Heart Association functional class IV; 13% had left main coronary artery stenosis; and 11% had preinfarction angina. On analysis of the early mortality, the limiting factor was diffuse coronary arteriosclerosis combined with poor ventricular function. This resulted in inadequate or incomplete myocardial revascularization. Since these two risk factors are usually predictable, coronary artery bypass can be recommended not only for patients with intractable angina, but also for patients with impaired left ventricular function associated with angina, and in patients without angina who have a positive stress electrocardiogram.
1969年至1974年期间,共有4522例患者接受了冠状动脉闭塞性疾病手术。本文对1974年接受手术的连续275例此类患者进行了深入分析。死亡率为1.8%,围手术期心肌梗死发生率为3.6%。在对危险因素进行分析时发现,24%的患者年龄超过60岁;57%的患者有一定程度的左心室功能障碍;9%的患者有广泛性心肌运动减弱;24%的患者为纽约心脏协会心功能IV级;13%的患者有左主干冠状动脉狭窄;11%的患者有梗死前心绞痛。在对早期死亡率进行分析时,限制因素是弥漫性冠状动脉硬化合并心室功能不良。这导致心肌血运重建不充分或不完全。由于这两个危险因素通常是可预测的,冠状动脉搭桥术不仅可以推荐给顽固性心绞痛患者,也可以推荐给伴有心绞痛的左心室功能受损患者,以及静息心电图阳性但无心绞痛的患者。