[血管舒缩功能障碍作为年轻受试者心血管疾病发生高风险的一个整体参数]
[Vegetovascular dysfunction as an integral parameter of high risk for cardiovascular diseases development in young subjects].
作者信息
Oteva E A, Nikolaeva A A, Nikolaev K Iu, Maslennikov A B, Pikovskaia N B, Lifshits G I
出版信息
Ter Arkh. 2000;72(4):31-4.
AIM
To study manifestations of vegetative dystonia in children of probands from families with hereditary IHD load regarding the main risk factors.
MATERIALS AND METHODS
44 individuals aged 21 +/- 0.7 years were selected out of 111 children from 103 examined families the fathers of which had transmural or macrofocal myocardial infarction at the age under 50. 22 of 44 examinees had syndrome of vegetovascular dystonia (VVD).
RESULTS
Children of probands with family history of cardiovascular disease and having VVD had levels of cholesterol, triglycerides and apoB higher, but HDLP cholesterol lower than those free of VVD. In daughters of the probands insulin and hydrocortisone levels were high whereas sons with VVD had only insulin levels higher.
CONCLUSION
Children of probands of both sexes had high coefficients of hormonal and metabolic adaptation dependent on the severity of VVD syndrome.
目的
研究具有遗传性缺血性心脏病负荷的家族中先证者子女的植物神经功能障碍表现及其主要危险因素。
材料与方法
从103个接受检查的家庭中的111名儿童中挑选出44名年龄为21±0.7岁的个体，这些家庭中孩子的父亲在50岁之前患有透壁性或大面积心肌梗死。44名受检者中有22名患有植物神经血管功能障碍综合征（VVD）。
结果
有心血管疾病家族史且患有VVD的先证者子女的胆固醇、甘油三酯和载脂蛋白B水平较高，但高密度脂蛋白胆固醇水平低于未患VVD的子女。先证者女儿的胰岛素和氢化可的松水平较高，而患有VVD的儿子只有胰岛素水平较高。
结论
取决于VVD综合征的严重程度，先证者的子女无论男女均有较高的激素和代谢适应系数。
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