López-Vélez R, Turrientes C, Baquero F, Mateos M L
Microbiology Department, Hospital Ramón y Cajal, Madrid, Spain.
Eur J Clin Microbiol Infect Dis. 2000 Apr;19(4):309-11. doi: 10.1007/s100960050482.
The aim of the present study was to investigate the prevalence of anti-hepatitis E virus (HEV) antibodies among indigenous Spanish blood donors and immigrants from developing countries in order to determine whether immigrants pose a significant risk for the transmission of HEV to the healthy Spanish population. The seroprevalence of HEV was determined in a cohort of 90 asymptomatic immigrants (mostly from countries in sub-Saharan Africa) who had recently arrived in Madrid, Spain, and in 863 blood donors, who represented the healthy Spanish population. The results showed that the prevalence of HEV antibodies was 1.9 times higher in the immigrants than in the blood donors (5.5% in immigrants, 95% CI 1.8-12.4; 2.9% in blood donors, 95% CI 1.9-4.2). Combined with the estimated population figures of 300,000 undocumented immigrants versus 39,000,000 Spaniards, these results indicate that sub-Saharan immigrants cannot currently be considered a major risk source for the transmission of HEV in Spain.
本研究的目的是调查西班牙本土献血者和来自发展中国家的移民中抗戊型肝炎病毒（HEV）抗体的流行情况，以确定移民是否对戊型肝炎病毒传播给健康的西班牙人群构成重大风险。在一组90名最近抵达西班牙马德里的无症状移民（大多来自撒哈拉以南非洲国家）和863名代表健康西班牙人群的献血者中测定了戊型肝炎病毒的血清流行率。结果显示，移民中戊型肝炎病毒抗体的流行率比献血者高1.9倍（移民中为5.5%，95%可信区间为1.8 - 12.4；献血者中为2.9%，95%可信区间为1.9 - 4.2）。结合30万无证移民与3900万西班牙人的估计人口数据，这些结果表明，目前撒哈拉以南移民不能被视为西班牙戊型肝炎病毒传播的主要风险来源。
