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多发性骨髓瘤累及心肌和冠状动脉血管。

Multiple myeloma involving the myocardium and coronary vessels.

作者信息

Champeaux A L, Blaser J L, Myers J B, Schachter D T

机构信息

Department of Pathology, Madigan Army Medical Center, Tacoma, WA 98431, USA.

出版信息

Arch Pathol Lab Med. 2000 Jun;124(6):910-2. doi: 10.5858/2000-124-0910-MMITMA.

Abstract

We report a case of metastatic plasmacytoma to the myocardium and coronary vessels in a 57-year-old man with multiple myeloma. Originally, the patient had a large plasmacytoma in his left chest wall and lung. He received local radiation and chemotherapy. Subsequently, the patient presented with symptoms of congestive heart failure. He had no prior history of cardiac disease. The patient was treated medically and later died from respiratory failure. At autopsy, a metastatic plasmacytoma was identified within the myocardium and externally compressing the coronary arteries. The tumor infiltrated into the coronary sinus. It is difficult to speculate whether the patient's symptoms were due to cardiac involvement since the tumor burden in his chest was also considerable. To our knowledge, coronary vessel involvement with plasmacytoma has not been previously described.

摘要

我们报告了一例57岁患有多发性骨髓瘤的男性患者,其心肌和冠状动脉发生转移性浆细胞瘤。最初,该患者左胸壁和肺部有一个大的浆细胞瘤。他接受了局部放疗和化疗。随后,患者出现充血性心力衰竭症状。他既往无心脏病史。该患者接受了药物治疗,后来死于呼吸衰竭。尸检时,在心肌内发现一个转移性浆细胞瘤,其外部压迫冠状动脉。肿瘤浸润至冠状窦。由于患者胸部的肿瘤负荷也相当大,很难推测其症状是否由心脏受累引起。据我们所知,此前尚未有浆细胞瘤累及冠状动脉的相关描述。

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