某些催产素类似物对大鼠的持久排乳作用。
Protracted milk-ejecting effect of some oxytocin analogues in rats.
作者信息
Barth T, Flegel M, Jost K
出版信息
Endocrinol Exp. 1976 Mar;10(1):65-71.
PMID:1083803
Abstract
Protracted effect of [2-0-methyltyrosine]-deamino-1-carba-oxytocin, [2-0-methyltyrosine]-oxytocin and its dimeric form was studied on the mammary gland of lactating rat in vivo. Biphasic course of biological response found for monomers and slow onset of response observed for dimer led to the assumption that the substances behaved like hormonogens.
摘要
研究了[2-0-甲基酪氨酸]-脱氨基-1-碳代催产素、[2-0-甲基酪氨酸]-催产素及其二聚体形式对泌乳大鼠乳腺的体内持久作用。单体呈现双相生物学反应过程，而二聚体观察到反应起效缓慢，这导致人们推测这些物质的行为类似于激素原。
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