Postma A, Meyer G, Tuiten A, van Honk J, Kessels R P, Thijssen J
Psychological Laboratory, Utrecht University, Department of Psychonomics, The Netherlands.
Psychoneuroendocrinology. 2000 Aug;25(6):563-75. doi: 10.1016/s0306-4530(00)00010-x.
Previous work has indicated that object-location memory is sensitive to sex differences as well as variations in the menstrual cycle. The goal of the present study was to further examine the hormonal basis of human spatial memory by assessing the effects of a single dose of exogenous testosterone in healthy young women on three recall conditions: positional reconstruction; object-to-position-assignment; and the combined condition in which subjects both have to reconstruct the precise locations and to link the different objects to the correct places. In the latter condition, delayed recall (3 min delay) improved with testosterone. Although the effects were only small and need further substantiation, they support the idea that testosterone may have an activational effect on selective aspects of cognitive functioning.
先前的研究表明，物体位置记忆对性别差异以及月经周期的变化很敏感。本研究的目的是通过评估单剂量外源性睾酮对健康年轻女性在三种回忆条件下的影响，进一步探究人类空间记忆的激素基础：位置重建；物体到位置的分配；以及受试者既要重建精确位置又要将不同物体与正确位置相联系的综合条件。在后一种条件下，睾酮使延迟回忆（延迟3分钟）得到改善。尽管这些影响很小且需要进一步证实，但它们支持了睾酮可能对认知功能的某些特定方面具有激活作用这一观点。
