Formigari R, Santoro G, Guccione P, Giamberti A, Pasquini L, Grigioni M, Ballerini L
Pediatric Cardiology and Cardiac Surgery, Ospedale Bambino Gesù, Rome, Italy.
Catheter Cardiovasc Interv. 2000 Jun;50(2):207-11. doi: 10.1002/(sici)1522-726x(200006)50:2<207::aid-ccd14>3.0.co;2-u.
The development of pulmonary artery stenosis is a potential complication during the mid- to long-term follow-up after arterial switch operation (ASO) for transposition of the great arteries. Surgical results have been disappointing and conventional balloon dilation yields a fairly important incidence of failures and recurrences. We evaluated our results with implantation of balloon-expandable stents in 5 out of 13 patients with a previously attempted unsuccessful conventional balloon dilation of pulmonary artery branch stenosis after ASO. In two more cases, stents were used as a primary procedure. Balloon angioplasty achieved a 15% increase in mean diameter of the stenosis vs. 124% with the use of stents (P< 0.01), a 10% decrease of the pressure gradient across the stenosis vs. 71% of stents (P<0.01), and a 10% drop in RV/aorta pressure ratio vs. 43% of stents (P<0.01). Compared to conventional balloon angioplasty in our series, stents were more effective in the treatment of patients with peripheral pulmonary artery stenosis after ASO. Balloon dilation should be considered in selected cases unsuitable for treatment with endovascular stents.
在大动脉转位的动脉调转手术(ASO)后的中长期随访期间,肺动脉狭窄的发展是一种潜在并发症。手术结果一直令人失望,传统的球囊扩张术失败和复发的发生率相当高。我们对13例曾尝试常规球囊扩张治疗ASO后肺动脉分支狭窄但未成功的患者中的5例植入球囊可扩张支架的结果进行了评估。另外2例中,支架被用作主要治疗手段。球囊血管成形术使狭窄平均直径增加了15%,而使用支架时增加了124%(P<0.01);狭窄两端压力阶差下降了10%,而使用支架时下降了71%(P<0.01);右心室/主动脉压力比值下降了10%,而使用支架时下降了43%(P<0.01)。与我们系列中的传统球囊血管成形术相比,支架在治疗ASO后外周肺动脉狭窄患者方面更有效。对于不适合血管内支架治疗的特定病例,应考虑球囊扩张术。