Gritti Michael N, Farid Pedrom, Hassan Ahmed, Marshall Audrey C
Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Division of Paediatric Cardiology, The Hospital for Sick Children, Toronto, ON, Canada.
Pediatr Cardiol. 2025 Feb;46(2):339-348. doi: 10.1007/s00246-024-03408-w. Epub 2024 Feb 10.
The arterial switch operation for d-transposition of the great arteries achieves anatomic repair but creates the potential for right ventricular outflow tract obstruction as a result of the LeCompte maneuver. The resultant right ventricular hypertension is generally well tolerated but a select group are referred for cardiac catheterization. The outcomes of these catheterizations have not been well described. The objective of this study was to describe the degree and nature of right ventricular outflow tract obstruction found during cardiac catheterization among patients following the arterial switch operation as well as determine the rate of intervention and assess the acute impact of any catheter intervention undertaken. We conducted a retrospective study of patients after arterial switch operation with the LeCompte maneuver and subsequent right heart catheterization. Descriptive statistics were reported, and paired sample t tests were used for analysis. 544 children had an arterial switch operation, of which 110 children (20%) had a cardiac catheterization procedure after surgery and 11% had a right heart catheterization. Of the right heart catheterizations, 90% had an intervention (balloon and/or stent). In the interventional group, the right ventricle to systemic pressure ratio decreased modestly, from 2/3 to half systemic, after balloon dilation and/or stent placement (p < 0.01). No serious complications were observed.
大动脉d型转位的动脉调转术可实现解剖修复,但由于LeCompte操作,会有导致右心室流出道梗阻的可能。由此产生的右心室高压通常耐受性良好,但有一部分患者需要进行心导管检查。这些导管检查的结果尚未得到充分描述。本研究的目的是描述动脉调转术后患者在心导管检查期间发现的右心室流出道梗阻的程度和性质,确定干预率,并评估所进行的任何导管干预的急性影响。我们对接受LeCompte操作及随后右心导管检查的动脉调转术后患者进行了一项回顾性研究。报告了描述性统计数据,并使用配对样本t检验进行分析。544名儿童接受了动脉调转术,其中110名儿童(20%)术后进行了心导管检查,11%进行了右心导管检查。在右心导管检查中,90%进行了干预(球囊和/或支架)。在干预组中,球囊扩张和/或支架置入后,右心室与体循环压力比适度下降,从2/3降至体循环的一半(p<0.01)。未观察到严重并发症。