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[血清素反应性脑结构在金黄仓鼠某些行为形式中的参与]

[Participation of the serotonin-reactive brain structure in certain forms of behavior in golden hamsters].

作者信息

Popova N K, Bertogaeva V D

出版信息

Farmakol Toksikol. 1975 Mar-Apr;38(2):148-51.

PMID:1084283
Abstract

A viviacious play of young hamsters is shown to be accompanied by a drop of the serotonin level in the brain stem and the subsequent slumber - by its rise, while the corticosteroids content of the peripheral blood with the playful behavior experiences no changes. Iprazid and 5-oxytryptophan inhibit the playful activity, while dioxyphenylalanina (DOPA) does not influence it. A similar depression of the serotonin level in the brain stem was also noted in an aggressive behavior and stress conditions arising when adult male-hamsters are grouped together. A conclusion is drawn to the effect that changes in the content of serotonin in the brain stem are not associated with the emotional colouration of the condition, but rather reflect the transition from the somnolence to a highly active behavior.

摘要

活泼的幼年仓鼠玩耍时,脑干中的血清素水平会下降,随后进入睡眠状态——血清素水平上升时则相反,而外周血中皮质类固醇的含量在玩耍行为期间并无变化。异卡波肼和5-羟色氨酸会抑制玩耍活动,而二羟基苯丙氨酸(多巴)则对其没有影响。在成年雄性仓鼠聚集在一起时出现的攻击行为和应激状态下,也观察到脑干中血清素水平有类似的降低。由此得出结论,脑干中血清素含量的变化与情绪状态无关,而是反映了从嗜睡到高度活跃行为的转变。

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