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组织细胞的被动致敏作用。V. 对嗜碱性粒细胞和嗜酸性粒细胞具有亲细胞性的鸡抗体的检测

Passive sensitization of tissue cells. V. The detection of chicken antibodies cytophilic for basophils and eosinophils.

作者信息

Wilson A B, Heller E D

出版信息

Int Arch Allergy Appl Immunol. 1976;51(1):68-79.

PMID:1084332
Abstract

Basophil-cytophilic antibodies were domonstrated in sera of chickens injected with either sheep erythrocytes or avian tuberculin. Normal chicken basophils were passively sensitized in vitro, and two types of cytophilic antibodies were shown by rosette-formation: (a) heat-stable, mercaptoethanol-resistant antibodies, and (b) heat-labile, mercaptoethanol-sensitive antibodies. Serum from one of the chickens injected with sheep erythrocytes also passively sensitized normal, non-basophilic granulocytes which would appear from stained smears to be eosinophils. Cytophilic activity in the serum correlated with the rosette-forming reactions of circulating eosinophils and/or basophils from each of the sensitized donor birds.

摘要

在注射了绵羊红细胞或禽结核菌素的鸡血清中证实了嗜碱性粒细胞亲细胞抗体。正常鸡嗜碱性粒细胞在体外被被动致敏,通过玫瑰花结形成显示出两种亲细胞抗体:(a)热稳定、巯基乙醇抗性抗体,和(b)热不稳定、巯基乙醇敏感抗体。注射了绵羊红细胞的一只鸡的血清也被动致敏了正常的非嗜碱性粒细胞,从染色涂片上看这些细胞似乎是嗜酸性粒细胞。血清中的亲细胞活性与来自每只致敏供体鸡的循环嗜酸性粒细胞和/或嗜碱性粒细胞的玫瑰花结形成反应相关。

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Passive sensitization of tissue cells. V. The detection of chicken antibodies cytophilic for basophils and eosinophils.组织细胞的被动致敏作用。V. 对嗜碱性粒细胞和嗜酸性粒细胞具有亲细胞性的鸡抗体的检测
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