Granger A, Sainsbury R, Wilkinson T, MacFarlane M
Department of Health Care of the Elderly, The Princess Margaret Hospital, Christchurch, New Zealand.
J Clin Neurosci. 2000 Mar;7(2):149-52. doi: 10.1054/jocn.1999.0171.
A case of a 69 year old woman with multiple meningiomas is presented. Since her first presentation with Jacksonian seizures in 1978, she has had 16 meningiomas excised in seven separate surgical procedures. This is extremely unusual due to both the large number of tumours, and the long period over which they have occurred. We review the epidemiology, possible pathogenesis and genetic associations of this condition.
本文报告了一例69岁患有多发性脑膜瘤的女性病例。自1978年首次出现杰克逊癫痫发作以来，她已通过七次单独的外科手术切除了16个脑膜瘤。鉴于肿瘤数量众多且发病时间跨度长，这种情况极为罕见。我们回顾了该疾病的流行病学、可能的发病机制及基因关联。
