Kouzu T, Miyazaki S, Yoshimura S, Hishikawa E, Kaiho Y
Department of Endoscopic Diagnostics and Therapeutics, Chiba University, Japan.
Nihon Geka Gakkai Zasshi. 2000 Apr;101(4):368-72.
We performed esophagocardioplasty with the gastric patch (original GP) as the treatment of first choice in patients with esophageal achalasia. However, postoperative reflux esophagitis occurred in many due to secretory dysfunction of the gastric mucosa implanted in the mediastinum. We therefore developed two modifications of the gastric patch technique (GP II and GP III) which do not involve implantation of the gastric mucosa in the esophagus. Twenty-three patients have undergone the modified GP II procedure in our institution. Postoperative changes in the esophagus were examined fluoroscopically, and it was found that esophageal diameter increased from an average 2.9 +/- 0.6 cm to 5.2 +/- 1.0 cm at an average follow-up of 7.1 months (p < 0.01). All 23 patients experienced amelioration of symptoms, even though some reddening was still present in the lower esophagus, with a maximum follow-up of 8 years. Based on these results, the modified GP procedures are an acceptable open surgery modality for esophagocardioplasty in esophageal achalasia.
我们采用带胃补片(原始胃补片)的食管贲门成形术作为贲门失弛缓症患者的首选治疗方法。然而,由于植入纵隔的胃黏膜分泌功能障碍,许多患者术后发生反流性食管炎。因此,我们对胃补片技术进行了两种改良(胃补片II和胃补片III),这两种改良方法不涉及将胃黏膜植入食管。我们机构中有23例患者接受了改良的胃补片II手术。通过荧光透视检查了术后食管的变化,发现在平均随访7.1个月时,食管直径从平均2.9±0.6厘米增加到5.2±1.0厘米(p<0.01)。所有23例患者症状均有改善,尽管食管下段仍有一些发红,最长随访时间为8年。基于这些结果,改良的胃补片手术是贲门失弛缓症食管贲门成形术可接受的开放手术方式。