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改良乙状结肠失弛缓症手术:一项技术细节的长期结果

Improving the surgery for sigmoid achalasia: long-term results of a technical detail.

作者信息

Faccani Enrico, Mattioli Sandro, Lugaresi Maria Luisa, Di Simone Massimo Pierluigi, Bartalena Tommaso, Pilotti Vladimiro

机构信息

Department of Surgery, Intensive Care, and Organ Transplantation, Division of Esophageal and Pulmonary Surgery Villa Maria Cecilia e San Pier Damiano Hospitals, Cotignola and Faenza (Ravenna), University of Bologna, Bologna, Italy.

出版信息

Eur J Cardiothorac Surg. 2007 Dec;32(6):827-33. doi: 10.1016/j.ejcts.2007.09.009. Epub 2007 Oct 10.

Abstract

OBJECTIVE

Heller myotomy results for the treatment of sigmoid achalasia are worse than those achieved for fusiform achalasia. We retrospectively examined two groups of sigmoid achalasia patients, in which we performed (1) the standard Heller-Dor procedure (no pull-down) and (2) the Heller-Dor plus a technique apt to obtain the verticality of the oesophageal axis (pull-down). We verified whether the latter technique improved long-term results.

MATERIALS AND METHODS

We considered 33 patients affected by primitive oesophageal sigmoid achalasia operated upon consecutively (1979-2005). Diagnosis was based on symptoms, manometry, radiology and endoscopy. After 1987, we routinely isolated 360 degrees of the gastro-oesophageal junction and the lower oesophagus and applied U stitches at the right side of the lower oesophagus to pull down and rotate the gastro-oesophageal junction toward the right. Fifteen patients underwent the no pull-down and 18 patients underwent the pull-down technique. Postoperative follow-up included objective clinical and instrumental evaluation (questionnaire filled by a surgeon including the assessment of symptoms and endoscopic reflux oesophagitis according to a semi-quantitative scale) and subjective evaluation (self-evaluation SF-36 questionnaire).

RESULTS

The mean follow-up period was 89 months (range 12-261 months). The postoperative dysphagia score was significantly improved in the entire group. Excellent results were present in 12 patients (36.4%), good in 11 (33.3%), fair in 3 (9.1%) and insufficient in 7 patients (21.2%). No statistically significant differences were observed between the two groups with regard to the postoperative symptoms and oesophagitis. Postoperative radiological measurements of oesophageal diameter and residual barium column were significantly improved in the whole group and within each group with respect to the radiological variables measured preoperatively (p=0.000). In the comparison of the two groups, statistically significant differences were observed with regard to mean oesophageal diameter (p=0.030) (pull-down, 4+/-0.9 cm; no pull-down, 4.7+/-0.6 cm) and residual barium column (p=0.048) (pull-down, 6.2+/-3.4 cm; no pull-down, 9.6+/-5.8 cm).

CONCLUSIONS

The Heller-Dor operation is effective in the presence of sigmoid achalasia. The clinical objective and subjective evaluations show a trend toward the improvement of results with the pull-down technique. Stronger statistical significance would probably be obtained from a larger case series.

摘要

目的

对于乙状结肠型贲门失弛缓症,海勒肌切开术的治疗效果比梭形贲门失弛缓症更差。我们回顾性研究了两组乙状结肠型贲门失弛缓症患者,一组接受(1)标准的海勒 - 多尔手术(无下拉操作),另一组接受(2)海勒 - 多尔手术加一种有助于使食管轴垂直的技术(下拉操作)。我们验证了后一种技术是否能改善长期治疗效果。

材料与方法

我们纳入了33例连续接受原发性食管乙状结肠型贲门失弛缓症手术治疗的患者(1979 - 2005年)。诊断基于症状、食管测压、放射学检查和内镜检查。1987年后,我们常规游离食管胃交界和食管下段360度,并在食管下段右侧应用U形缝线,将食管胃交界向下牵拉并向右侧旋转。15例患者接受无下拉操作,18例患者接受下拉技术。术后随访包括客观的临床和器械评估(由外科医生填写问卷,包括根据半定量量表评估症状和内镜下反流性食管炎)以及主观评估(自我评估SF - 36问卷)。

结果

平均随访时间为89个月(范围12 - 261个月)。整个组术后吞咽困难评分显著改善。12例患者(36.4%)效果极佳,11例(33.3%)良好,3例(9.1%)尚可,7例患者(21.2%)效果欠佳。两组在术后症状和食管炎方面未观察到统计学显著差异。与术前测量的放射学变量相比,整个组以及每组内食管直径和残留钡柱的术后放射学测量值均显著改善(p = 0.000)。在两组比较中,观察到食管平均直径(p = 0.030)(下拉组,4 ± 0.9 cm;无下拉组,4.7 ± 0.6 cm)和残留钡柱(p = 0.048)(下拉组,6.2 ± 3.4 cm;无下拉组,9.6 ± 5.8 cm)存在统计学显著差异。

结论

海勒 - 多尔手术对乙状结肠型贲门失弛缓症有效。临床客观和主观评估显示下拉技术有改善治疗效果的趋势。更大样本量的病例系列可能会获得更强的统计学显著性。

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