Drug Ther Bull. 2000 Apr;38(4):31-2. doi: 10.1136/dtb.2000.38431.
One of the more disruptive symptoms of eczema is itching. Traditionally, it is treated with emollients, topical corticosteroids or oral antihistamines. A topical form of the antidepressant doxepin (doxepin 5% cream; Xepin-Bioglan) is now marketed for "the relief of pruritus associated with eczema" in adults and children aged over 12 years. Here, we review the efficacy and safety of this product and assess its role in the management of eczema.
湿疹最具破坏性的症状之一是瘙痒。传统上，它通过润肤剂、外用皮质类固醇或口服抗组胺药进行治疗。一种外用形式的抗抑郁药多塞平（5%多塞平乳膏；Xepin-Bioglan）目前已上市，用于缓解12岁及以上成人和儿童“与湿疹相关的瘙痒”。在此，我们回顾该产品的疗效和安全性，并评估其在湿疹管理中的作用。
