Suarez-Varel M M, Martinez-Selva M I, Llopis-Gonzalez A, Martinez-Jimeno J L, Plaza-Valia P
Unit of Clinical Epidemiology, Hygiene & Environmental Care, University of Valencia, Spain.
Eur J Epidemiol. 2000 Feb;16(2):193-8. doi: 10.1023/a:1007630903188.
Spontaneous pneumothorax (SP) is a common respiratory condition that is easily recognized and treated, though the etiology remains largely unknown. Apart from individual factors, it has been suggested that changes in atmospheric pressure may trigger the onset of SP. Our aim was to examine the association between the onset of episodes of SP with atmospheric pressure changes in the general population of an area with a Mediterranean climate. A prospective survey was conducted to detect all episodes of SP in a region of Valencia (Spain) from January 1994 to January 1996. A total of 69 cases were identified; of these, 62 episodes of SP met the inclusion criteria for this survey. Climatic measurements during the two years studied were obtained from the Spanish National Meteorological Institute, including 6-hour readings of temperature, relative humidity, clear sunlight, atmospheric pressure, visibility, wind speed and rainfall. Associations were evaluated between the daily number of hospital admissions for SP and diurnal changes in atmospheric pressure involving rises and falls of as much as 7 and 10 mbar. In addition, the association of atmospheric pressure changes to time periods of 1 a.m., 7 a.m., 1 p.m. and 7 p.m. was assessed. Drops in atmospheric pressure below the fifth percentile and elevations above the ninety-fifth percentile were regarded as 'unusual'. There was no association between the development of SP and changes in atmospheric pressure, and no correlation was found with repeated exposure to unusual changes of atmospheric pressure. Further research is needed using similar methods to establish comparisons between countries with different climates.
自发性气胸(SP)是一种常见的呼吸系统疾病,虽病因大多不明,但易于识别和治疗。除个体因素外,有观点认为大气压力变化可能引发SP发作。我们的目的是研究地中海气候地区普通人群中SP发作与大气压力变化之间的关联。1994年1月至1996年1月期间,在西班牙巴伦西亚地区进行了一项前瞻性调查,以检测所有SP发作病例。共识别出69例病例,其中62例SP发作符合本调查的纳入标准。所研究的两年期间的气候测量数据来自西班牙国家气象研究所,包括温度、相对湿度、日照、大气压力、能见度、风速和降雨量的每6小时读数。评估了SP每日住院人数与大气压力昼夜变化(变化幅度高达7至10毫巴)之间的关联。此外,还评估了大气压力变化与凌晨1点、早上7点、下午1点和晚上7点时间段的关联。大气压力降至第五百分位数以下和升至第九十五百分位数以上被视为“异常”。SP的发生与大气压力变化之间无关联,且未发现与反复暴露于异常大气压力变化之间存在相关性。需要采用类似方法进行进一步研究,以对不同气候国家进行比较。