[不同病理情况下的冷淋巴细胞毒素]

[Cold lymphocytotoxins in various pathological situations].

作者信息

Prou O, d'Ambrosio A M, Muller J Y

出版信息

Rev Fr Transfus Immunohematol. 1975 Dec;18(4):351-60. doi: 10.1016/s0338-4535(75)80025-0.

Abstract

Cold lymphocytotoxins have been described extensively in many situations. In the present work, this kind of antibody has been found less frequently than previously in some diseases like infectious mononucleosis, rheumatoïd arthritis, or kidney transplanted patients. These discrepancies may be due to technical considerations. In contrast, cold lymphocytotoxins, in the present work, have been frequently detected in auto-immune hemolytic anemias with cold agglutinins, and in patients having immuno-deficiencies.

摘要

冷淋巴细胞毒素在许多情况下已有广泛描述。在本研究中，这种抗体在某些疾病（如传染性单核细胞增多症、类风湿性关节炎或肾移植患者）中的发现频率低于以往。这些差异可能是由于技术因素。相比之下，在本研究中，冷淋巴细胞毒素在伴有冷凝集素的自身免疫性溶血性贫血患者以及免疫缺陷患者中经常被检测到。