Zimmermann C, Baldo C, Molino A
Dipartimento di Medicina e Sanità Pubblica, Servizio di Psicologia Medica, Università di Verona, Italy.
Breast Cancer Res Treat. 2000 Mar;60(1):9-14. doi: 10.1023/a:1006342316373.
To examine the effects of framing of outcome and probabilities of cancer occurrence on the treatment preference which breast cancer patients indicate for hypothetical patient scenarios.
A modified version of the Decision Board Instrument (Levine et al. 1992) was administered to 35 breast cancer patients with past ACT experience. Patients expressed their choice regarding ACT for six scenarios which were characterized by either negative or positive framing of outcome and by one of the three levels of probability of recurrence (high, medium, low).
The framing had no influence on ACT choices over all three probability levels. The majority chose ACT for high and medium risk and one third switched from ACT to No ACT in the low-risk condition. This switch was statistically significant.
Hypothetical treatment decisions against ACT occur only when the probability of recurrence is low and the benefit of ACT is small. This finding for patients with past experience of ACT is similar to those reported for other oncological patient groups still in treatment.
探讨结果的呈现方式以及癌症发生概率对乳腺癌患者针对假设患者情景所表明的治疗偏好的影响。
对35名有过辅助化疗（ACT）经历的乳腺癌患者使用了决策板工具（Levine等人，1992年）的修改版。患者对六种情景表达了他们对辅助化疗的选择，这些情景的特征是结果呈现为消极或积极，以及复发概率的三个水平之一（高、中、低）。
在所有三个概率水平上，呈现方式对辅助化疗的选择没有影响。大多数人在高风险和中等风险时选择辅助化疗，在低风险情况下，三分之一的人从辅助化疗转向不进行辅助化疗。这种转变具有统计学意义。
只有当复发概率低且辅助化疗的益处小时，才会出现反对辅助化疗的假设治疗决策。这一针对有辅助化疗经历患者的发现与仍在接受治疗的其他肿瘤患者群体的报告结果相似。
