Hahn U, Swanson A A, Hockwin O
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1976 May 26;199(3):197-206. doi: 10.1007/BF00417288.
A longitudinal study has been conducted on three exopeptidases which include an esterase, leucine aminopeptidase, and a triglycinopeptidase and two endopeptidases, a neutral protease and a proteinase or catheptic activity in bovine lenses. The esterase and leucine aminopeptidase behave similarily showing increased activities with aging. Triglycinopeptidase has a somewhat lower order of magnitude when compared to the other exopeptidases. The neutral protease shows initially high activity early in the developmental life period, whereas, the proteinase or catheptic activity indicates a continuous increase with aging. Data whereas, the proteinase or catheptic activity indicates a continuous increase with aging. Data is also provided on enzymic activity in the different sections of the lens which include the combined anterior cortex and epithelium, lens nucleus, posterior cortex, and equatorial ring.
对牛晶状体中的三种外肽酶（包括一种酯酶、亮氨酸氨肽酶和一种三甘氨肽酶）以及两种内肽酶（一种中性蛋白酶和一种具有蛋白酶或组织蛋白酶活性的酶）进行了一项纵向研究。酯酶和亮氨酸氨肽酶表现相似，随着年龄增长活性增加。与其他外肽酶相比，三甘氨肽酶的活性数量级略低。中性蛋白酶在发育生命周期早期活性最初较高，而蛋白酶或组织蛋白酶活性则表明随着年龄增长持续增加。还提供了晶状体不同部分（包括联合前皮质和上皮、晶状体核、后皮质和赤道环）的酶活性数据。
