Sugiyama Y, Honma M, Yamamoto T
Department of Neurology, School of Medicine, Fukushima Medical University.
Intern Med. 2000 Jun;39(6):486-9. doi: 10.2169/internalmedicine.39.486.
Following a high fever, a healthy woman became comatose within a few days. Severe cerebellar symptoms appeared when she regained consciousness. The brain MRIs revealed abnormal signal intensity of the cerebellar cortex and brainstem gray matter, however, no abnormalities were revealed in the cerebral hemispheres. Acute inflammation due to direct viral or autoimmune involvement of the cerebellar and brainstem gray matter was a likely explanation and thus acute cerebellitis may in fact be a rhombencephalitis. Among the previous reports of acute cerebellar ataxia, this is perhaps one of the most profoundly affected cases and appears important for the understanding of the target of this particular form of encephalitis.
一名健康女性在高烧后几天内陷入昏迷。苏醒后出现了严重的小脑症状。脑部磁共振成像显示小脑皮质和脑干灰质信号强度异常,然而,大脑半球未发现异常。小脑和脑干灰质直接受到病毒或自身免疫影响导致的急性炎症可能是一个合理的解释,因此急性小脑炎实际上可能是一种菱脑炎。在之前关于急性小脑共济失调的报告中,这可能是受影响最严重的病例之一,对于理解这种特殊形式的脑炎的靶点似乎很重要。