Ivezić S, Bagarić A, Oruc L, Mimica N, Ljubin T
Psychiatric Hospital Vrapce, Zagreb, Croatia,
Croat Med J. 2000 Jun;41(2):179-83.
To investigate the prevalence rate of post-traumatic stress disorder (PTSD) comorbid psychiatric disorders and to explore psychotic symptoms in patients with combat-related current PTSD.
The sample included Croatian war veterans (N=41) who were hospitalized at the University Department of Psychiatry of the Vrapèe Psychiatric Hospital during the 1995-1996 period and fulfilled the DSM-IV criteria for the current and chronic PTSD. The Schedule for Affective Disorder and Schizophrenia (SADS-L) was applied for the assessment of current and lifetime psychiatric disorders. Only three subjects had a prewar Axis I psychiatric disorder. One third of the patients met the criteria for personality disorder.
After severe combat trauma, the majority of PTSD patients (33/41) had at least one comorbid psychiatric diagnosis on Axis I. In those with personality disorders the most frequent was alcohol dependence, whereas in those without personality disorders it was major depressive disorder. Psychotic symptoms occurred in 8 out of 41 PTSD patients. None of them had a primary psychotic disorder or a personality disorder. In all the patients, psychotic symptoms were different from flashbacks. They were symbolically related to the trauma and resistant to antipsychotic treatment. Psychotic symptoms were associated with depression in 5 out of 8 patients with psychotic symptoms.
Severe and prolonged combat trauma may be followed by the co-occurrence of PTSD and psychotic symptoms, forming the atypical clinical picture of PTSD.
调查创伤后应激障碍(PTSD)合并精神障碍的患病率,并探讨与战斗相关的当前PTSD患者的精神病性症状。
样本包括1995 - 1996年期间在弗拉佩精神病医院大学精神科住院的克罗地亚退伍军人(N = 41),他们符合当前和慢性PTSD的DSM-IV标准。应用情感障碍和精神分裂症量表(SADS-L)评估当前和终生精神障碍。只有三名受试者有战前轴I精神障碍。三分之一的患者符合人格障碍标准。
在经历严重战斗创伤后,大多数PTSD患者(33/41)至少有一种轴I合并精神科诊断。在有人格障碍的患者中最常见的是酒精依赖,而在无人格障碍的患者中最常见的是重度抑郁症。41名PTSD患者中有8人出现精神病性症状。他们中没有人患有原发性精神病性障碍或人格障碍。在所有患者中,精神病性症状与闪回不同。它们与创伤有象征意义的关联,对抗精神病药物治疗有抵抗性。8名有精神病性症状的患者中有5人,其精神病性症状与抑郁有关。
严重和长期的战斗创伤可能会导致PTSD和精神病性症状同时出现,形成PTSD的非典型临床表现。