Bogolepova I N, Malofeeva L I
Laboratory of Brain Anatomy and Architecture, Russian Academy of Medical Sciences, Moscow.
Morfologiia. 2000;117(2):13-8.
Cytoarchitecture of speech areas 44 and 45 of human brain was studied on frontal series of sections of brain of a newborn, 6 months, 1 year and 2 years old child. Sections were stained with cresyl violet after Nissl. Density of neurons and gliocytes location as well as fraction of satellite gliocytes and surrounded by the latter, glia index were determined by quantitative methods. General principles of cortical areas 44 and 45 were distinguished as well as peculiarities of their formation if left and right hemispheres of human brain in postnatal ontogenesis. Heterochronia of postnatal development of areas 44 and 45 was demonstrated. A hypothesis on different activity of right and left hemispheres speech areas in different periods of speech development of the child was discussed.
对一名新生儿、6个月、1岁和2岁儿童大脑额叶切片系列进行研究，以观察人类大脑言语区44和45的细胞结构。切片经尼氏染色后用甲酚紫染色。通过定量方法确定神经元和神经胶质细胞的密度、位置以及卫星神经胶质细胞的比例和被后者包围的情况，即神经胶质指数。区分了皮质区44和45的一般原则以及人类大脑左右半球在出生后个体发育过程中其形成的特点。证实了区域44和45出生后发育的异时性。讨论了关于儿童言语发展不同时期左右半球言语区不同活动的假说。
