Créange A
Service de neurologie et laboratoire Germen, (INSERM E.0011) Hôpital Henri-Mondor, Créteil.
Rev Prat. 2000 Apr 1;50(7):743-8.
Infective neuropathies constitute a leading cause of neuropathies in the world. The number of patients with nerve lesions related to leprosy remains high despite decreasing number of new cases requiring multidrug regimens. Peripheral neuropathies associated with HIV infection may be found in up to 50% of patients. Neuropathies may be related to the inflammatory reaction against viral antigens, immunodepression, opportunistic infections, and iatrogenic complications of anti-viral drugs. Hepatitis C virus infection has been found in cryoglobulinemic neuropathies. This virus should be screened for exploration of all neuropathies. Rare causes of neuropathy, such as poliomyelitis and diphtheria, and treatable neuropathies such as Lyme disease, should not be forgotten.
感染性神经病是全球神经病的主要病因。尽管需要多药联合治疗的新病例数量在减少，但与麻风病相关的神经病变患者数量仍然居高不下。高达50%的HIV感染患者可能会出现周围神经病。神经病可能与针对病毒抗原的炎症反应、免疫抑制、机会性感染以及抗病毒药物的医源性并发症有关。在冷球蛋白血症性神经病中发现了丙型肝炎病毒感染。对于所有神经病的检查都应筛查该病毒。不应忘记神经病的罕见病因，如脊髓灰质炎和白喉，以及可治疗的神经病，如莱姆病。
