Léger J M, Hoang-Xuan K
Fédération de neurologie Mazarin, Hôpital de La Salpêtrière, Paris.
Rev Prat. 2000 Apr 1;50(7):753-8.
Peripheral neuropathies associated to cancers encompass several causes: entrapment or direct involvement of peripheral nerves, paraneoplastic and non tumoral causes, mainly infectious, metabolic or carential. Paraneoplastic neuropathy is mainly the so-called sensory ganglionopathy. A purely motor neuronopathy may be observed in Hodgkin's disease and "terminal" polyneuropathy may complicate may known cancer, in a context of severe weight loss. Polyneuropathies associated with paraproteinaemia include those associated with a defined lymphoproliferative disorder (myelomas, solitary plasmocytoma, Waldenström's disease, lymphoma), and associated with monoclonal gammopathy of undetermined significance.
周围神经受压或直接受累、副肿瘤性和非肿瘤性病因，主要是感染性、代谢性或营养缺乏性。副肿瘤性神经病变主要是所谓的感觉神经节病。在霍奇金病中可观察到纯运动神经元病，在严重体重减轻的情况下，“终末期”多发性神经病可能使多种已知癌症复杂化。与副蛋白血症相关的多发性神经病包括与特定淋巴增殖性疾病（骨髓瘤、孤立性浆细胞瘤、华氏巨球蛋白血症、淋巴瘤）相关的以及与意义未明的单克隆丙种球蛋白病相关的。
