Tormene A P, Riva C
Department of Ophthalmology, University of Padova, Padua, Italy.
Doc Ophthalmol. 1998;96(4):347-54. doi: 10.1023/a:1001720210698.
The aim was to evaluate alterations in Visual-Evoked Potentials (VEP) and Electroretinogram (ERG) and discover whether these tests are useful for determining residual visual acuity in cases where a patient is unable to collaborate. Flash and, when possible, Transient Pattern Reversal Visual-Evoked Potentials and Maximal Response ERG were recorded in 8 children (under three years old) affected by different aspects of optic nerve coloboma. None of them had visual acuity evaluated because of poor collaboration. All examinations were carried out using skin electrodes. Amplitude of the a and b component of ERG, amplitude, morphology and latency of the major components of Flash VEP and amplitude and latency of P100 Pattern Reversal VEP were evaluated. Four of the patients were examined three years later and visual acuity was compared with the previous electrofunctional results. Alterations in ERG were found only in the case of significant retinal anomalies (great coloboma, retinal detachment), huge alterations were found in both Flash VEP and in Pattern Reversal VEP. The retrospective study of VEP traces and visual acuity showed a good correlation between electrofunctional data and visual capability. Electrofucntional examinations can identify important conductive retinocortical anomalies. The possibility of correlating electrophysiological results with residual visual acuity is important for rehabilitative management in such optic disc malformations.
目的是评估视觉诱发电位（VEP）和视网膜电图（ERG）的变化，并确定这些检查在患者无法配合的情况下对于确定残余视力是否有用。对8名受视神经缺损不同方面影响的儿童（3岁以下）记录了闪光以及尽可能记录瞬态图形翻转视觉诱发电位和最大反应ERG。由于配合不佳，他们均未进行视力评估。所有检查均使用皮肤电极进行。评估了ERG的a和b成分的振幅、闪光VEP主要成分的振幅、形态和潜伏期以及P100图形翻转VEP的振幅和潜伏期。其中4名患者在3年后接受检查，并将视力与之前的电功能检查结果进行比较。仅在存在明显视网膜异常（大缺损、视网膜脱离）的情况下发现ERG有变化，在闪光VEP和图形翻转VEP中均发现了巨大变化。对VEP痕迹和视力的回顾性研究表明，电功能数据与视觉能力之间存在良好的相关性。电功能检查可以识别重要的视网膜皮质传导异常。将电生理结果与残余视力相关联的可能性对于此类视盘畸形的康复管理很重要。
