异烟肼治疗所致新生儿吡哆醇反应性惊厥
Neonatal pyridoxine responsive convulsions due to isoniazid therapy.
作者信息
McKenzie S A, Macnab A J, Katz G
出版信息
Arch Dis Child. 1976 Jul;51(7):567-8. doi: 10.1136/adc.51.7.567.
Abstract
A 17-day-old infant on isoniazid therapy 13 mg/kg daily from birth because of maternal tuberculosis was admitted after 4 days of clonic fits. No underlying infective or biochemical cause could be found. The fits ceased within 4 hours of administering intramuscular pyridoxine, suggesting an aetiology of pyridoxine deficiency secondary to isoniazid medication.
摘要
一名17天大的婴儿因母亲患肺结核，自出生起每日接受13毫克/千克的异烟肼治疗。在出现阵挛性惊厥4天后入院。未发现潜在的感染或生化原因。在肌内注射维生素B6后4小时内惊厥停止，提示病因是异烟肼用药继发的维生素B6缺乏。
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