Cullen C L, Grahn B H
Department of Veterinary Internal Medicine, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon.
Can Vet J. 2000 Jun;41(6):470-80.
The prevalence of equine glaucoma seen by the ophthalmology service at the Western College of Veterinary Medicine (WCVM) was 6.5%. The majority of cases (11/13) were associated with clinical manifestations of uveitis. Congenital glaucoma was documented in 1 case, and primary glaucoma was diagnosed in a 12-year-old quarter horse. There were no breed or sex predilections evident. Affected horses were middle-aged to old (average age = 9.5 years, ranging from 2 weeks to 23 years). The clinical manifestations of equine glaucoma included blindness, diffuse corneal edema, corneal vascularization, buphthalmia, corneal striae, recurrent secondary ulcerative keratitis, and less commonly, iris bombé, tapetal hyper-reflectivity, complete pupillary occlusion from posterior synechiae, and optic disc cupping. Elevated intraocular pressure confirmed the diagnosis (n = 10), while 3 cases were normotensive with signs of glaucoma including corneal striae and buphthalmia. Affected eyes were treated medically and/or surgically. Regardless of the therapy instituted, the visual outcome was poor. Most affected eyes were blind at presentation or became blind within a few weeks.
西部兽医学院(WCVM)眼科服务所诊治的马青光眼患病率为6.5%。大多数病例(11/13)与葡萄膜炎的临床表现相关。有1例记录为先天性青光眼,1例12岁的夸特马被诊断为原发性青光眼。未发现明显的品种或性别偏好。患病马匹为中年至老年(平均年龄 = 9.5岁,范围从2周龄至23岁)。马青光眼的临床表现包括失明、弥漫性角膜水肿、角膜血管化、眼球增大、角膜条纹、复发性继发性溃疡性角膜炎,较少见的有虹膜膨隆、视网膜反光增强、后粘连导致的完全瞳孔闭塞以及视盘杯状凹陷。眼内压升高确诊了10例病例,而3例眼压正常但有青光眼体征,包括角膜条纹和眼球增大。患病眼睛接受了药物和/或手术治疗。无论采取何种治疗方法,视力预后都很差。大多数患病眼睛在就诊时已失明或在几周内失明。