Fielding H, Kyaterekera N, Skellern G G, Tettey J N, McDade J R, Msuya Z, Watson D G, Urie J
Western General Hospital, Edinburgh.
Palliat Med. 2000 May;14(3):205-7. doi: 10.1191/026921600666997498.
Varying concentrations of octreotide acetate (Sandostatin) and diamorphine hydrochloride were prepared and stored in polypropylene syringes at 37 degrees C in the dark. The solutions were analysed for octreotide acetate content using a validated HPLC method at regular intervals over a 48-h period. The results indicate that octreotide acetate remains stable in the presence of diamorphine hydrochloride at 37 degrees C for 24 h. In addition, the solutions prepared maintained their clarity, with no signs of precipitation upon visual examination under normal light conditions.
制备了不同浓度的醋酸奥曲肽（善宁）和盐酸二氢吗啡酮，并将其置于聚丙烯注射器中，于37℃黑暗条件下储存。在48小时内定期使用经过验证的高效液相色谱法分析溶液中的醋酸奥曲肽含量。结果表明，在37℃下，醋酸奥曲肽在盐酸二氢吗啡酮存在的情况下可保持24小时稳定。此外，所制备的溶液保持澄清，在正常光照条件下目视检查无沉淀迹象。
