Pendleton R G, Sherman S S
Arch Int Pharmacodyn Ther. 1976 Jul;222(1):94-102.
Dopamine is both diuretic and saluretic in the conscious rat. The diuretic effect does not appear to be beta-receptor mediated, but rather may be the result of a combination of alpha- and dopaminergic receptor stimulation. Conclusive proof for the existence of the latter, however, must await the discovery of a more selective peripheral dopamine-receptor stimulant than is dopamine per se.
多巴胺对清醒大鼠具有利尿和促尿钠排泄作用。其利尿作用似乎不是由β受体介导的,而可能是α受体和多巴胺能受体刺激共同作用的结果。然而,要确凿证明后者的存在,必须等待发现一种比多巴胺本身更具选择性的外周多巴胺受体兴奋剂。