Chopra R, Radotra B D, Varma S, Gupta K L, Joshi K
Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Indian J Pathol Microbiol. 1999 Jul;42(3):375-8.
Acute pneumonitis with diffuse alveolar haemorrhage is potentially fatal. When it occurs in a patient of systemic lupus erythematosus, the primary disease itself may be responsible for it; rather than any complicating infection or metabolic/physiological derangement. Diagnosis of primary pulmonary involvement by systemic lupus erythematosus can only be made on open lung biopsy coupled with immunofluorescent and/or ultrastructural studies. Early diagnosis of acute pulmonary complications in systemic lupus erythematosus patients is essential as specific management is reported to improve the chances of recovery.
伴有弥漫性肺泡出血的急性肺炎有潜在致命性。当它发生在系统性红斑狼疮患者身上时,原发性疾病本身可能是病因;而非任何并发感染或代谢/生理紊乱。系统性红斑狼疮所致原发性肺部受累的诊断只能通过开胸肺活检并结合免疫荧光和/或超微结构研究来做出。系统性红斑狼疮患者急性肺部并发症的早期诊断至关重要,因为据报道,针对性治疗可提高康复几率。