Mathur A N, Hourtovenko C D, Baigrie R S, Mecci S U, Ravi G D, Garg R
Sudbury Regional Hospital and Laurentian University, Canada.
Can J Cardiol. 2000 Jun;16(6):747-56.
To examine the controversial issues of postoperative aortic insufficiency (AI), operative mortality and length of hospital stay (LOS) following stentless Freestyle aortic valve replacement (AVR).
All surgeries were performed in a small northern community hospital (Sudbury Regional Hospital, Sudbury, Ontario).
Retrospective study of all stentless AVRs and all stented AVRs from May 1996 to December 1998, and isolated coronary artey bypasses (CABGs) done in 1996/97.
Patients were not selected. All consecutive patients requiring bioprosthetic AVR during this period, regardless of risk, complexity or urgency, were included. In total, 112 stentless AVRs, 138 stented AVRs and 432 isolated CABGs were examined.
AI was rare following stentless AVRs: no significant valvular AI and only 0.9% significant paravalvular AI occurred. The incidence of AI was significantly greater with continuous than with interrupted proximal suturing (P=0. 016). No valve thromboses, thromboemboli or structural failure occurred during 3.8 years of follow-up of the stentless AVRs. The LOS for stentless AVRs was no longer than for stented AVRs or for isolated CABGs. No significant difference was found in the operative mortality following stentless and stented AVRs. The early mortality rate of 1.8% for stentless AVRs was not affected by preoperative risk strata, complexity or urgency.
Early morbidity with stentless AVRs was comparable and LOS was no longer than with stented AVRs. The use of Freestyle bioprosthesis in itself did not result in greater operative mortality, regardless of risk, complexity or urgency of the procedure. Consistent reproducible techniques and experience improve postoperative outcome. It is essential that potential users carefully learn safe and effective surgical techniques to avoid adverse outcomes during the learning curve.
探讨无支架Freestyle主动脉瓣置换术(AVR)术后主动脉瓣关闭不全(AI)、手术死亡率及住院时间(LOS)等存在争议的问题。
所有手术均在加拿大安大略省萨德伯里市北部的一家小型社区医院(萨德伯里地区医院)进行。
对1996年5月至1998年12月期间所有无支架AVR和所有有支架AVR以及1996/1997年进行的单纯冠状动脉旁路移植术(CABG)进行回顾性研究。
未进行患者选择。纳入在此期间所有需要生物人工心脏瓣膜置换术的连续患者,无论其风险、复杂程度或紧急程度如何。总共检查了112例无支架AVR、138例有支架AVR和432例单纯CABG。
无支架AVR术后AI罕见:无明显瓣膜性AI,仅发生0.9%的明显瓣周漏。连续近端缝合的AI发生率显著高于间断近端缝合(P = 0.016)。在对无支架AVR进行3.8年的随访期间,未发生瓣膜血栓形成、血栓栓塞或结构破坏。无支架AVR的住院时间不超过有支架AVR或单纯CABG。无支架AVR和有支架AVR术后的手术死亡率无显著差异。无支架AVR的早期死亡率为1.8%,不受术前风险分层、复杂程度或紧急程度的影响。
无支架AVR的早期发病率相当,住院时间不超过有支架AVR。无论手术的风险、复杂程度或紧急程度如何,使用Freestyle生物人工心脏瓣膜本身并不会导致更高的手术死亡率。一致可重复的技术和经验可改善术后结果。潜在使用者必须仔细学习安全有效的手术技术,以避免在学习曲线期间出现不良后果。