Rowland R W
University of California San Francisco, USA.
Ann Periodontol. 1999 Dec;4(1):65-73; discussion 78. doi: 10.1902/annals.1999.4.1.65.
Necrotizing periodontal diseases are unique in their clinical presentation and course. Data suggest that the etiology and pathogenesis of necrotizing periodontal diseases may also be distinctive from other periodontal diseases. Necrotizing ulcerative gingivitis (NUG) is a type of necrotizing periodontal disease in which the necrosis is limited to the gingival tissues. Three specific clinical characteristics must be present to diagnose NUG, pain (usually of rapid onset) interdental necrosis, and bleeding. Epidemiological and prospective clinical studies have found an altered ability to cope with psychological stress, immunosuppression, and tobacco use to be strongly associated with the onset of NUG.
坏死性牙周疾病在临床表现和病程方面独具特色。数据表明,坏死性牙周疾病的病因和发病机制可能也有别于其他牙周疾病。坏死性溃疡性龈炎(NUG)是坏死性牙周疾病的一种类型,其坏死仅限于牙龈组织。诊断NUG必须具备三个特定的临床特征:疼痛(通常起病迅速)、牙间坏死和出血。流行病学及前瞻性临床研究发现,应对心理压力能力的改变、免疫抑制和吸烟与NUG的发病密切相关。