Sun C, Zhong M, Wang Z, Wang Y
Department of Oral and Maxillofacial Surgery, First Affiliated Hospital, China Medical University (CMU), P. R. China.
Chin J Dent Res. 1999 Dec;2(3-4):65-7.
To study the possibility of neuroendocrine feature of salivary adenoid cystic carcinoma (SACC).
Immunohistochemical staining was operated in SACC with S-100 protein, neurospecific enolase (NSE), chromogranin A, and synaptophysin, which are specific and correlative with neuroendocrine cells and neoplasias.
The positive expression of S-100, NSE, chromogranin, and synaptophysin were 42, 32, 8, and 7, respectively, in 50 cases of SACC.
Neuroendocrine feature in some SACC cells is possibly indicated.
研究涎腺腺样囊性癌(SACC)的神经内分泌特征的可能性。
采用免疫组织化学染色法检测SACC中与神经内分泌细胞及肿瘤相关的特异性标志物S-100蛋白、神经特异性烯醇化酶(NSE)、嗜铬粒蛋白A和突触素。
50例SACC中,S-100、NSE、嗜铬粒蛋白和突触素的阳性表达分别为42例、32例、8例和7例。
部分SACC细胞可能具有神经内分泌特征。