Blumlein S L, Anderson A J, Barboriak J J, Rimm A A, Walker J, Flemma R
J Thorac Cardiovasc Surg. 1976 Nov;72(5):778-83.
The relationship between graft patency and the presence of presurgical prognostic factors was studied in 636 patients who have undergone aorta-coronary bypass operation. We have found a positive correlation between vein graft patency and both coronary artery constriction score (p less than 0.01) and diastolic blood pressure (p less than 0.05). In patients studied up to one year after surgery, high graft patency was associated with both higher diastolic pressures (p less than 0.03) and higher cholesterol levels (p less than 0.001). However, high cholesterol levels also were associated with coronary arterial obstruction. In patients studied more than a year after operation, high constriction scores before the operation were associated with improved graft patency (p less than 0.03). Our findings indicate that short-term prognosis of the grafts is related mainly to hemodynamic variables.
在636例接受主动脉-冠状动脉搭桥手术的患者中,研究了移植血管通畅性与术前预后因素之间的关系。我们发现静脉移植血管通畅性与冠状动脉狭窄评分(p<0.01)和舒张压(p<0.05)均呈正相关。在术后长达一年的研究患者中,高移植血管通畅性与较高的舒张压(p<0.03)和较高的胆固醇水平(p<0.001)相关。然而,高胆固醇水平也与冠状动脉阻塞有关。在术后一年以上的研究患者中,术前高狭窄评分与移植血管通畅性改善相关(p<0.03)。我们的研究结果表明,移植血管的短期预后主要与血流动力学变量有关。