Time between sputum examination and treatment in patients with smear-negative pulmonary tuberculosis.

The time between sputum examination and commencement of treatment in patients registered with smear-negative pulmonary tuberculosis (PTB) in four hospitals in Malawi was investigated. Information was obtained in 701 of 887 patients who were registered over a 12-month period between 1997 and 1998: 86% were started on treatment within 3 weeks of sputum examination, 14% were started after a 3-week interval and 6% after a 6-week interval. Such delays are unacceptable, for a number of reasons. Recommendations will go to programme staff to repeat sputum examination in PTB suspects with an abnormal chest radiograph whose negative sputum smears were examined more than 3 weeks previously.