Holper K, Gams E, Schmidt-Habelmann P, Kunkel R, Richter J, Sebening F
Thoraxchir Vask Chir. 1976 Oct;24(5):373-7. doi: 10.1055/s-0028-1095948.
A total of 47 infants (2,7 to 9,6 kg in weight, 3 days to 21 months of age, 89% under one year) underwent early total correction of severe congenital heart defects in profound hypothermia of about 22degreesC and circulatory arrest (11 to 64 minutes). 8 patients were operated upon without extracorporeal circulation (ECC) (mortality 63%). 37 infants were additionally cooled and rewarmed with ECC (mortality 22%). The most common diagnosis were: Total atrioventricular canal (11), aortic stenosis with and without combined lesions (8), tetralogy of Fallot (7), ventricular septum defect (7) and transposition of the great arteries (4).
共有47例婴儿(体重2.7至9.6千克,年龄3天至21个月,89%为1岁以下)在约22摄氏度的深度低温和循环停止(11至64分钟)下接受了严重先天性心脏缺陷的早期完全矫正。8例患者在无体外循环(ECC)的情况下接受手术(死亡率63%)。37例婴儿另外通过ECC进行降温及复温(死亡率22%)。最常见的诊断为:完全性房室通道(11例)、伴有或不伴有合并病变的主动脉狭窄(8例)、法洛四联症(7例)、室间隔缺损(7例)以及大动脉转位(4例)。