Hammond D
Lincolnland Home Care of Sarah Bush Lincoln, Mahoon, IL.
J Intraven Nurs. 1999 Nov-Dec;22(6):331-5.
CytoGam is a hyperimmune globulin created specifically for prophylactic use when a cytomegalovirus seronegative patient receives an organ from a seropositive donor. CytoGam is derived from human pooled plasma rich with cytomegalovirus antibodies, immunoglobulin G, and trace amounts of immunoglobulin A and immunoglobulin M. Clinical studies show a marked decrease in the development of cytomegalovirus when transplant recipients are treated with CytoGam. CytoGam also has undergone trial testing for use in decreasing the instance of cytomegalovirus in patients with human immune deficiency virus (HIV). CytoGam therapy may continue for several months, making home intravenous care essential.
赛妥珠单抗是一种超免疫球蛋白，专为预防巨细胞病毒血清学阴性的患者接受血清学阳性供体的器官时使用而制备。赛妥珠单抗源自富含巨细胞病毒抗体、免疫球蛋白G以及微量免疫球蛋白A和免疫球蛋白M的人混合血浆。临床研究表明，移植受者接受赛妥珠单抗治疗后，巨细胞病毒感染的发生率显著降低。赛妥珠单抗还进行了用于降低人类免疫缺陷病毒（HIV）患者巨细胞病毒感染发生率的试验测试。赛妥珠单抗治疗可能持续数月，因此家庭静脉护理至关重要。
